Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-04-23
1998-09-29
MacMillan, Keith D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514478, 514479, 514546, 514547, 514552, 514625, 514629, 514380, A61K 3127, A61K 31335, A61K 3122, A61K 31225
Patent
active
058146598
ABSTRACT:
The present invention comprises a topical analgesic composition comprising an analgesic agent, an alcohol, a chaotropic agent and an unsaturated fatty acid. The composition is preferably in the form of a stable gel and may further comprise a pharmaceutically acceptable emulsifier, a pharmaceutically acceptable gelling and/or thickening agent, and a pharmaceutically acceptable preservative. The pH of the composition is adjusted to 7.5-8.0 by the addition of a pharmaceutically acceptable organic base, such as triethanolamine.
The invention also comprises a method for inducing topical analgesia. The composition is absorbed on an absorbent material, for example a cotton strip inserted into typical skin-wipe packet; brought in contact with the skin of a person in need of such an analgesia; and maintained in contact with the skin for a period of time sufficient to induce and maintain topical analgesia.
REFERENCES:
patent: 5482965 (1996-01-01), Rajadhyaksha et al.
Kling, J.W. and Riggs, L.A., Editors, Woodworth & Schlosberg's Experimental Psychology, 3rd. edition, pp. 154-166, Holt, Rinehart and Winston, Inc., New York, N.Y. (1971).
Anchordoguy, T.J. et al., Effects of Protein Perturbants on Phospholipid Bilayers, Arch. Biochem. Biophys. 283: 356 (1990).
Behl, C.R. et al. Age and Anatomical Site Influence on Alkanol Permeation of Skin of the Male Hairless Mouse, J. Soc. Cosmet. Chem., 35: 237 (1984).
Rowe, E.S., Lipid Chain Length and Temperature Dependence of Ethanol-Phosphatidyl Choline Interactions, Biochemistry 22: 3299 (1983).
Chemical Abstracts AN 1993:160285, Wohlrab, Jan. 1992.
Chemical Abstracts AN 1989:13572,Mahjour et al., Jan. 1989.
Chemical Abstracts AN 1993:546514, Gaspulin et al., 1993.
DTR Dermal Therapy (Barbados) Inc.
MacMillan Keith D.
LandOfFree
Topical analgesic composition does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Topical analgesic composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Topical analgesic composition will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-686735