Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1993-11-15
1994-09-13
Hook, Gregory
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514647, A61K 3710, A61K 31135
Patent
active
053468864
ABSTRACT:
The invention provides a pharmaceutical composition for the treatment of a mammal having a skin disease. The composition contains a serine protease inhibitor and an effective amount of a cationic quaternary ammonium salt at a concentration below the critical micelle concentration for increasing the penetration of the inhibitor in the skin. Additionally, these may be included an ethoxylated nonylphenol.
REFERENCES:
patent: 5008242 (1991-04-01), Lezdey
patent: 5134119 (1992-07-01), Lezdey
patent: 5166134 (1992-11-01), Lezdey
patent: 5190917 (1993-03-01), Lezdey
patent: 5217951 (1993-06-01), Lezdey
Hubbard et al, "Biochemical Efficacy and Safety of Monthly Augmentation Therapy for Alpha 1-Antitrypsin Deficiency" JAMA, vol. 260, No. 9, Sep. 2, 1988.
Remington Pharmaceutical Sciences p. 730, 1159, 1985.
Lezdey John
Wachter Allan
Hook Gregory
Lezdey John
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