Topical administration of vitamin D to mammals

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai

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514947, A61K 31595

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active

055322298

ABSTRACT:
A method of delivering a nutritional or therapeutic amount of vitamin D to the blood of a mammal, which method comprises topically administering to the skin of the mammal a vitamin D nutritionally or therapeutically-effective amount of a composition comprising a nutritional or therapeutically effective amount of vitamin D in a suitable pharmaceutically-acceptable carrier, diluent or adjuvant therefor and compositions therefor. The method provides a more suitable, safer and efficient way of providing a mammal with its daily vitamin D intake.

REFERENCES:
patent: 2060228 (1991-11-01), Lorenz
patent: 3981996 (1976-09-01), Leigh
patent: 4310511 (1982-01-01), Holick
patent: 4335120 (1982-06-01), Holick et al.
patent: 5380528 (1995-01-01), Alban et al.
Skin Care Products: A and D Ointments (1992).
Holick, et al: "The Production of 1.alpha.,25-Dihydroxyvitamin D, in Skin"; The New England Journal of Medicine, vol. 303, No. 7, Aug. 14, 1980, pp. 349-354.
Haddad et al: "Human Plasma Transport of Vitamin D after its Endogenous Synthesis", The American Society for Chemical Investigation, Inc., vol. 91, Jun. 1993, pp. 2552-2555.

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