Topical administration of amifostine and related compounds

Details Topical administration of amifostine and related compounds Topical administration of amifostine and related compounds

2006-12-19

2006-12-19

Kim, Vickie (Department: 1618)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

C514S114000, C514S573000, C514S665000, C514S740000

Reexamination Certificate

active

07151094

ABSTRACT:
The present invention is directed to methods of treating or protecting mucosal tissue from damage associated with radiation and/or chemotherapeutic treatment of cancers, by the topical application of amifostine and related compounds. These methods avoid the side effects of systemically applied radio/chemo protectants. The invention is also directed to treatment and prevention of infections associated with mucositis by topical application of amifostine and related compounds.

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