Toothpastes

Details Toothpastes Toothpastes

1988-08-18

1990-06-19

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Fluorine or fluorine compound containing

424 49, A61K 716, A61K 718

Patent

active

049352270

ABSTRACT:
The invention relates to a toothpaste containing a therapeutic agent through the use of which there is produced a sustained and enhanced level of the therapeutic agent in the oral fluids. The toothpaste comprises 30 to 75% by weight of an abrasive cleaning agent consisting at least in part of calcium carbonate, a therapeutic agent, 0.01 to 0.6% by weight of a flavouring agent, and 0.002 to 0.1% by weight of sodium saccharinate or the equivalent amount of another sweetening agent.

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Derwent WPI Acc No. 85-138981/23 Lion Corp, JPN 60075415, 4/27/85, Dentifrice . . ., "Calcium-Free Abrasive".
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Schrader's `Grundlagen u. Rezepturen der Kosmetika`, p. 415, 1979, "Some Aspects of the Kinetics of Fluoride in Saliva", J. Ekstrand, F. Lagerloff and A. Oliveby, pp. 91-98, 1986.
J. Dent Res. 66(2): 430-435, Feb., 1987.

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