Tooth whitening formulation and method

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices

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424 49, 424 53, 424 54, A61K 3340, A61K 910, A61K 4738, A61K 600

Patent

active

052905667

ABSTRACT:
A tooth whitening formulation comprising urea peroxide (1:1) in a concentration of 22-32% based on the total weight of the formulation, in combination with a gelling agent, is provided in accordance with the present invention. The invention also provides a method for whitening the teeth using said formulation wherein the formulation is applied to the teeth using a splint which keeps the formulation in contact with the teeth for a period of time sufficient to cause whitening thereof.

REFERENCES:
patent: 4983379 (1991-01-01), Schaeffer
patent: 4988500 (1991-01-01), Hunter et al.
patent: 4990089 (1991-02-01), Munro
patent: 5008106 (1991-04-01), Meriands et al.
patent: 5009885 (1991-04-01), Yarborough
Bowles W., Thompson L., "Vital Bleaching: The Effects of Heat and Hydrogen Peroxide on Pulpal Enzymes", Journal of Endodontics, 12 No. 3: 108-122 (1986).
Epstein S., "Clinical Comparison . . . ", Oral Surgery, 32 No. 6:886-890 (1971).
Feinman R. A., Goldstein R. E., Garber D. A., "Bleaching Teeth", Quintessence, Chicago Publishing Co., Inc. (1987).
McCloskey R. J., "A Technique for Removal of Fluorosis Stains", Journal of American Dental Association, 109:63-64 (1984).
Baumgartner J., Reid D., Pickett A., "Human Pulpal Reaction to the Modified McInnes Bleaching Technique", Journal of Endodontics, 9:527-9 (1983).
Titley K., Torneck C., Smith D., "Effects of Concentrated Hydrogen Peroxide Solutions on the Surface Morphology of Human Tooth Enamel", Journal of Endodontics, 14, No. 2:69-74 (1988).
Bowles W., "Pulp Chamber Pentration by Hydrogen Peroxide Following Vital Bleaching", Journal of Endodontics, 12, No. 8:375-377 (1987).
Haywood et al, Nightguard Vital Bleaching, Quintessence International 20; 1989; pp. 173-176.

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