Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-02-10
1994-09-20
Henley, III, Raymond J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514356, 514458, A61K 3135, A61K 3144, A61K 31355
Patent
active
053489748
ABSTRACT:
This invention relates to the use of tocotrienol, gamma-tocotrienol and delta-tocotrienol in reducing hypercholesterolemia, hyperlipidemia and thromboembolic disorders in mammals. The isolation of these tocotrienols from natural sources and their chemical synthesis is disclosed. The present invention also relates to prodrugs and pharmaceutical compositions of gamma-tocotrienol, delta-tocotrienol and tocotrienol and uses thereof.
REFERENCES:
patent: 4603142 (1986-07-01), Burger et al.
The Nutrition Desk Reference, Garrison et al., (1985) p. 100.
Tan, "Palm Carotenoids, Tocopherols and Tocotrienols" JAOCS, vol. 66, No. 6 (Jun. 1989) pp. 770-776.
Parker Rex
Pearce Bradley C.
Qureshi Asaf A.
Wright John J.
Bristol--Myers Squibb Company
Henley III Raymond J.
Hoffman Frank P.
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