Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...
Patent
1992-07-17
1995-07-11
Naff, David M.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
435125, 435132, 435156, C12N 900, C12P 1706, C12P 700, C12P 722
Patent
active
054320690
ABSTRACT:
A tocopherol cyclase is produced in homogenous form which acts on phytyl benzoquinol derivatives to produce R', R', R'-tocopherols enantioselectively. The cyclase has a molecular weight of from about 48 kD to about 50 kD as determined by SDS-PAGE. The cyclase is isolated from Chlorella protothecoides, Dunaliella salina and wheat leaves of the Fidel variety.
REFERENCES:
patent: 2640058 (1953-05-01), Weisler
patent: 3819657 (1974-06-01), Baldwin et al.
patent: 4115949 (1978-09-01), Avron et al.
patent: 4554390 (1985-11-01), Curtain et al.
patent: 4582919 (1986-04-01), Barner et al.
patent: 4709055 (1987-11-01), Barner et al.
patent: 4958460 (1990-09-01), Nielson et al.
Henry et al., "Intermediates of Tocopherol biosynthesis in the Unicellulor alga Scenedesmus obliquus", Biochem. J. 242, 367-373, 1987.
Dasilva et al., "Content of .alpha.-Tocopherol in some Blue-green algae", Biochimica et Biophysica Acta, vol. 239, 1971pp. 345-347.
Whistance et al., "Biosynthesis of Phytoquinones", Biochemical Journal, vol. 117, 1970 pp. 593-600.
Drokova et al., "The content of Tocopherol in Alga Dunaliella salina", Ukr. Bot. Zh, vol. 31(2) pp. 229-231, 1974.
Johnson et al., Journal of Bacteriology, 95(4), 1461-1468 (1968).
Yamamoto, Yoshikazu, et al., Chemical Abstracts, vol. 110, No. 9, Abstract No. 73888v, p. 507 (Feb. 27, 1989), JP 62,186,789.
Agency of Industrial Sciences and Technology, Chemical Abstracts, vol. 99, No. 21, Abstract No. 174542, p. 516 (Nov. 21, 1993), JP 58 99,475.
Gruninger Fiona
Hochuli Erich
Matzinger Peter K.
Gould George M.
Hoffmann-La Roche Inc.
Johnston George W.
Meller Michael
Naff David M.
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