Tocols as adjuvant in vaccine

Details Tocols as adjuvant in vaccine Tocols as adjuvant in vaccine

1994-10-07

1997-07-22

Woodward, Michael P.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Lipid or oil

4242041, A61K 9107, A61K 3912, A61K 31355

Patent

active

056501552

ABSTRACT:
Oil based vaccines often cause serious local side effects at the site of administration and/or have a high viscosity which make said vaccines difficult to handle. Vaccines comprising as an adjuvant a stable emulsion of tocols in water do not display these undesired effects and induce good immune responses.

REFERENCES:
patent: 3919411 (1975-11-01), Glass et al.
patent: 4650677 (1987-03-01), Roerink et al.
patent: 4772466 (1988-09-01), Allison et al.
patent: 4788056 (1988-11-01), Lutticken et al.
patent: 5151267 (1992-09-01), Babiuk et al.
Merck Index, pp. 1290, 889, 327, (1976).
Tengerdy, et al, 1983, "Vitamin-E Enhanced Humoral Antibody . . . " Br. Vet. J. 139:147-152.
Allison, et al, 1988, "An Adjuvant Formulation for Use with . . . " Technological Advances in Vaccine Development, pp. 401-409.
Afzal, et al, 1984, "Protection of Rams Against Epididymihs . . . " Vet. Immunol. & Immunopath 7:293-304.
Tengerdy, et al, 1983, "Vitamin-E Enhanced Humoral . . . " British Veterinary Journal 139:147-52.
Franchini, et al., 1988 "Use of Vitamin E in the Preparation . . . " Clinica Veterinaria 111:121-133.

Affiliated with

Also associated with

Rating

Tocols as adjuvant in vaccine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tocols as adjuvant in vaccine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tocols as adjuvant in vaccine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1558622