Tobacco smoking inhibitor

Details Tobacco smoking inhibitor Tobacco smoking inhibitor

1981-02-06

1982-01-19

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Chewing gum type

426 3, 426548, 426650, 131270, A61K 968

Patent

active

043116914

ABSTRACT:
A composition comprising a gamma pyrone, such as maltol or ethyl maltol, and an inert carrier capable of providing sustained release of the gamma pyrone in the mouth, is useful for inhibiting tobacco smoking.

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Fenaroli's Handbook of Flavor Ingredients, 2nd Ed. (1971), CRC Press, Cleveland, Ohio, p. 179, Ethyl Maltol (up to 50 ppm), p. 327, Maltol (up to 90 ppm).
C.A. 76 #70329g (1972), 78 #70236i (1973), 79 #76032p (1973), 81 #62300j (1974), 82 #14177t (1975), 82 #15330z (1975), C.A. 83 #190530g (1975), 86 #21718f (1977), 86 #145665f, #145679p (1977), 87 #4312x, #4313y (1977), 88 #16851p (1978).
Larson, P. S., Silvette, H., Tobacco Experimental & Clinical Studies Suppl. 2, Wilkins and Wilkins, Co., Balto. MD, 1971: 246-248, 543-545, Esp 543:Gould, (1953), Noted that Medicated Lozenge Curbed Smoking:Benzocaine Flavored w/Saccharin, Licorice, Ginger, Anise, Wintergreen, Peppermint, Coriander and Cloves (no citation given).
Opdyke, D. L. J., Food Cosmet. Toxicol. 13, Suppl., 805-806 (1975) Ethyl Maltol.
Opdyke, D. L. J., Food Cosmet. Toxicol. 13, Suppl., 841 (1975) Maltol.
Aoyagi, N., Chem. Pharm. Bull. 22, 1008 (1974).
Brantmark, B., et al., Psychopharmacologia Berl. 31, 201 (1973).
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Merry, J. & Preston G., The Practitioner (May 1963), pp. 629-631.
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Shumacher, J. N. et al., J. Agric. Food Chem. 1977, 310.
Sutherland, A., et al., J. Consulting Clin. Psych., pp. 443-447 (Aug. 1975).
USPHS, 1976, Adult Use of Tobacco-1975.

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