Tobacco – Antismoking product or device – i.e. – deterent
Patent
1979-10-09
1981-07-07
Rose, Shep K.
Tobacco
Antismoking product or device, i.e., deterent
424 48, 426 3, 426660, A61K 968
Patent
active
042768900
ABSTRACT:
A method of inhibiting or destroying the desire to smoke tobacco products which comprises administering for an extended period of time a gamma pyrone selected from the class of maltol and ethyl maltol and in a quantity initially of not less than about 500 milligrams per day. By incorporating a maltol in relatively large amounts in gum, candy, or other physiologically acceptable media, the desired amount of maltol can be taken by reasonable daily consumption of such media. Releasing the maltol in the mouth at least 10 minutes for about 12 to 15 times per day is important. A lozenge or troche that lasts over 10 minutes in the mouth and releases ethyl maltol at a rate of excess of about 0.2 mg./min. is preferred. When this is done the pyrone should be administered at more than about 75 mg./day.
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Fernaroli's Handbook of Flavor Ingredients, 2nd Ed. (1971), CRC Press, Cleveland, Ohio, p. 179 Ethyl Maltol (up to 50 ppm), pp. 327 Maltol (up to 90 ppm).
C. A. 76 #70329q (1972) 78, #70236r (1973) 79 #76032p (1973) 81, #62300d (1974) 82, #14177t (1975) 82, #15330z (1975).
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Larson, P. S., Silvette, H., Tobacco, Experimental & Clinical Studies Supplement 2, Williams & Wilkins Co. Balt. Md 1971:246-248, 543-545 p. 543, esp. Gould (1953), noted that medicated lozenge curbed smoking, Benzocaine Flavored with Saccharin, Licorice, Ginger, Anise, Wintergreen, Peppermint, Coriander & Cloves (No Citation Given).
Opdyke, D. L. J. Food Cosmet. Toxicol. 13, Suppl. 805-806 (1975), Ethyl Maltol, Suppl. 841 (1975), Maltol.
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