Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Reexamination Certificate
2005-03-24
2008-10-07
Kemmerer, Elizabeth C. (Department: 1649)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
C530S387300, C530S388230, C530S391300, C424S133100, C424S134100, C424S135100, C424S136100, C435S069100, C435S069700, C435S070210, C435S252300, C435S254110, C435S455000
Reexamination Certificate
active
07431927
ABSTRACT:
The invention provides monoclonal antibodies that neutralize TNFα activity. The monoclonal antibodies may be rabbit monoclonal antibodies or monoclonal antibodies having CDR regions derived from those rabbit monoclonal antibodies. In certain embodiments, the monoclonal antibodies may be humanized. Methods of using the subject antibodies to inhibit TNFα activity, methods of treatment using those antibodies and kits containing the same are also provided. The invention finds use in a variety of research and medical applications.
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Couto Fernando Jose Rebelo Do
Hendricks Kristin Beth
Wallace Stacey Ellen
Bozicevic Field & Francis LLP
Emch Gregory S
Epitomics, Inc.
Keddie James S.
Kemmerer Elizabeth C.
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