Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Reexamination Certificate
2007-08-21
2007-08-21
O'Hara, Eileen B. (Department: 1646)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
C424S198100, C530S327000, C530S317000, C514S002600, C514S015800
Reexamination Certificate
active
10162553
ABSTRACT:
The present invention is based on the finding that peptides derived from a specific domain of tumor necrosis factor-alpha (TNF-α) can efficiently be used to treat oedema. More specifically, the present invention relates to the usage of peptides derived from the region of human TNF-α from Ser100to Glu116to treat pulmonary oedema. For example, the circularized peptide having amino acid sequence CGQRETPEGAEAKPWYC is shown to be very efficient in inducing oedema resorption.
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Bloc Alain
De Baetselier Patrick
Fransen Lucie
Lucas Rudolf
Pugin Jerome
Innogenetics N.V.
O'Hara Eileen B.
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