Tivozanib response prediction

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S091200, C536S024310, C536S024330

Reexamination Certificate

active

07615353

ABSTRACT:
A diagnostic method for predicting quantitatively whether a human tumor will be responsive or resistant (non-responsive) to treatment with the VEGF inhibitor, tivozanib (AV-951), is disclosed. The test is based on application of an algorithm to measurements of expression levels of the genes in a predictive gene set.

REFERENCES:
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patent: WO-2007/028005 (2007-03-01), None
patent: WO-2008/128008 (2008-10-01), None
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