Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone
Patent
1994-11-09
1997-03-11
Prebilic, Paul B.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
Bone
606 76, 523113, 523115, A61F 228
Patent
active
056096330
ABSTRACT:
A bone substitute, which provides both the fracture toughness of titanium or titanium alloys and the bioactivity of apatite, wherein titanium or titanium alloys and apatite are tightly adhered, is produced by soaking a substrate of titanium or titanium alloy in an alkaline solution to form a layer comprising amorphous alkali titanate, followed by the heating of the said substrate up to at most the titanium or titanium alloy transition temperature so as to form a stabilized amorphous alkali titanate layer and a sufficient concentration gradient of alkali and titanium ions to permit the growth of apatite thereon from solutions containing apatite-containing ions.
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patent: 4801300 (1989-01-01), Kurze et al.
patent: 4965088 (1990-10-01), Shimamune et al.
Kasemo, Biocompatibility of Titanium Implants: Surface Science Aspects, Jun. 1983, J. of Pros. Dent., vol. 49, No. 6, pp. 832-837.
"An Introduction to Bioceramics", Hench et al., World Scientific, vol. 1, (1993), pp. 223-238.
"The role of hydrated silica, titania, and alumina in inducing apatite on implants", Li et al., Journal of Biomedical Materials Research, vol. 28, (1994), pp. 7-15.
"Surface Preparation and Corrosion Behavior of Titanium Alloys for Surgical Implants", Fraker et al., ASTM Special Technical Publication, vol. 796, (1981), pp. 206-219.
"The Growth Kinetics and Optical Properties of Films Formed Under Open Circuit Conditions on a Titanium Surface in Potassium Hydroxide Solutions", Corrosion Science, vol. 33 (1), (1992), pp. 153-164.
Prebilic Paul B.
The Foundation for Promotion of Ion Engineering
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