Tissue viability monitor

Surgery – Truss – Pad

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Details

128664, 128665, 128666, A61B 500

Patent

active

054977703

ABSTRACT:
A method and apparatus for evaluating the viability of a tissue of interest, particularly that presents as dead but may be merely stunned or hibernating with reduced or no contractility. Dynamic measurement of oxidative metabolism permits distinguishing between different stages of compromised myocardium. Measurements can be made using near-infrared illumination and detection coupled with infusion of one or more metabolic substrates to the region of interest to evaluate whether a metabolic pathway cascade or a trans-membrane ionic potential are intact and thereby provide an indication of the viability of the cell.

REFERENCES:
patent: 4223680 (1980-09-01), Joebsis
patent: 4281645 (1981-08-01), Joebsis
patent: 4513751 (1985-04-01), Abe et al.
patent: 4693255 (1987-09-01), Beall
patent: 4877034 (1989-10-01), Atkins et al.
patent: 5054916 (1991-10-01), Kanda et al.
patent: 5074306 (1991-12-01), Green et al.
patent: 5127408 (1992-07-01), Parsons et al.
patent: 5161531 (1992-11-01), Parsons et al.
patent: 5227308 (1993-07-01), Jameson et al.
R. J. Barnard, et al., "Studies of Controlled Reperfusion After Ischemia--III. Histochemical studies: Inability of triphenyltetrazolium chloride nonstaining to define tissue necrosis," J. Thorac. Cardiovasc. Surg., 92:502-12 (1986).
M. R. Milunski, et al., "Ultrasonic Tissue Characterization With Integrated Backscatter," Circulation, 80:491-503 (1989).
N. C. Morcos et al., "(CA.sup.2+ +Mg.sup.2+)-ATPase in enriched sarcolemma from dog heart," Biochim. Biophys. Acta, 598:27-39 (1980).
N. C. Morcos, "Localization of (CA.sup.2+ +Mg.sup.2+)-ATPase, CA.sup.2+ pump and other ATPase activities in cardiac sarcolemma," Biochim. Biophys. Acta, 688:747-56 (1982).
W. J. Parsons et al., "Dynamic Mechanisms of Cardiac oxygenation during brief ischemia and reperfusion," J. Physiol. Heart Circ. Physiol., vol. 259(5):H1477-85 (1990).

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