Chemistry: molecular biology and microbiology – Vector – per se
Patent
1995-06-27
1997-12-16
Stone, Jacqueline M.
Chemistry: molecular biology and microbiology
Vector, per se
4351723, 4352401, 4352402, 4352523, 514 2, 514 44, 424 9321, A61K 4800, C12N 500, C12N 1500
Patent
active
056984430
ABSTRACT:
Host cell specific adenovirus vehicles are provided for transfecting target host cells. By providing for transcriptional initiating regulation dependent upon transcription factors that are only active in specific, limited cell types, virus replication will be restricted to the target cells. The modified adenovirus may be used as a vehicle for introducing new genetic capability, particularly associated with cytotoxicity for treating neoplasia.
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Henderson Daniel Robert
Schuur Eric Rodolph
Calydon, Inc.
Milne Andrew K.
Stone Jacqueline M.
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