Tissue specific adenovirus vectors for breast cancer treatment

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514 44, 514 1, 4353201, A01N 4304, A01N 6100, C12N 1500

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active

060967188

ABSTRACT:
Replication defective adenoviral vectors serve as vehicles for genes encoding products that kill cells in which the genes are transferred and activated. The novel vectors include tissue specific promoters, and are successful in targeting mammalian cancer cells, in particular human breast cancer cells, and causing tumors to regress.

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