Tissue re-surfacing with hydrogel-cell compositions

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis

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623 12, 623 13, 623 15, 623 16, 602 48, 602 49, 604 28, 604290, A61F 202, A61F 208, A61F 204, A61F 210, A61F 1300, A61M 100

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059447540

ABSTRACT:
The invention provides compositions and methods for generating new tissue on a surface, e.g., a surface of damaged or lost tissue, of a structure or organ in a mammal, The methods involve applying a thin layer of a liquid hydrogel-cell composition to the surface; and allowing the liquid hydrogel-cell composition to solidify, thereby forming a matrix that enables the tissue precursor cells to grow and generate new tissue. The surface can be internal, e.g., the surface of an organ or the internal surface of a blood vessel, or external, e.g., skin.

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