Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Reexamination Certificate
2005-10-17
2008-08-12
Hartley, Michael G. (Department: 1618)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
Reexamination Certificate
active
07410634
ABSTRACT:
Various pathophysiological states are determined by evaluating the rate of17O-containing water production oxygen using proton MRI. The method can be used to identify viable but threatened myocardium, injured by viable muscle, penumbra tissue in a stroke patient, and the like.
REFERENCES:
patent: 4996041 (1991-02-01), Arai et al.
patent: 5339814 (1994-08-01), Lasker
patent: 5682883 (1997-11-01), Fiat
patent: 6280383 (2001-08-01), Damadian
patent: 6727697 (2004-04-01), Fiat
patent: 6792302 (2004-09-01), Wintermark et al.
Heiss et al. (Stroke 2004, Supp. 1, 2671-2674).
Warach (Stroke 2003, 24, 2533-2534).
Arai, M.D. et al., Critical Care Medicine, vol. 17, pp. 1333-1334 (1989).
Rogers et al., “T2 Imaging using O-17 for Detection of Viability in Myocardial Infarction”, International Society of Magnetic Resonance in Medicine Seventh Annual Meeting, Philadelphia, U.S.A. (May 1999).
Sobesky, M.D. et al., Stroke, vol. 36, pp. 980-985 (2005).
C.P. Derdeyn, MD, et al., “Cerebral hemodynamic impairment: Methods of measurement and association with stroke risk,” Neurology, vol. 53(2), Jul. 22, 1999, pp. 251-259.
Bradley et al., “Blood flow and oxygen extraction fraction in regions of oedema following head injury”, Critical Care, vol. 8, Suppl. 1, p. 311 (2004).
Study of “Measurement of Cerebral Oxygen Extraction Fraction Using MRI Technique”, by Yuan-Heng Mo, M.D. (Jul. 2004).
Yamauchi et al., Journal of Neurology Neurosurgery and Psychiatry, vol. 75, pp. 33-37 (2004).
Derdeyn et al., Stroke, vol. 29, pp. 754-758 (1998).
An et al., Magnetic Resonance in Medicine, vol. 47, Issue 5, pp. 958-966 (2002).
Ansorge et al., Proc. Intl. Soc. Mag. Reson. Med., vol. 11, p. 1794 (2003).
Young et al., J. Cereb. Blood Flow Metab., vol. 16, No. 6, pp. 1176-1188 (1996).
Delapaz Robert Louis
Gupte Pradeep M.
Dickstein & Shapiro LLP
Hartley Michael G.
Perreira Melissa
Rockland Technimed Ltd.
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