Tissue irrigating solutions

Details Tissue irrigating solutions Tissue irrigating solutions

1992-07-13

1993-06-22

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Phosphorus or phosphorus compound

424665, 424678, 424679, 424680, 424681, 424717, 514 2, 514 23, 514554, 514562, 514665, 514912, A61K 3342, A61K 3314, A61K 3300, A61K 3700, A61K 3170, A61K 31205, A61K 31195, A61K 3113

Patent

active

052215377

ABSTRACT:
Irrigating solutions with thiol or disulfide containing compounds in physiologically acceptable salt solutions are described. The irrigating solutions are useful during surgery, particularly ophthalmic, neural, cardiovascular or otic surgery, to stabilize the affected tissue. Methods for their preparation and use are described.

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Martindale, The Extra Pharmacopoeia (28th ed. 1982) p. 50.
McEnerney et al., "Simplification of Glutathione Bicarbonate Ringer Solution Its Effect on Corneal Thickness," Investigative Ophthalmology and Visual Science, 16(7), Jul., 1977.
Meister, "Selective Modification of Glutathione Metabolism," Science, vol. 220, No. 4596, pp. 472-477, Apr., 1983.
O'Malley, "Salt Contamination of the Eye, an Infusion Hazard," Ocutome/Fragmatome Newsletter, vol. 4(14), 1979.
J. Worst, American Intraocular Implant Society Journal, (Jan., 1978).

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