Tissue implant systems and methods for sustaining viable high ce

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424422, 623 66, A61F 202

Patent

active

055934404

ABSTRACT:
A method for implanting cells is disclosed which employs a chamber having a wall forming porous boundary between the host and implanted cells. According to the method, a given number of cells (N) is placed within the porous boundary of a given area (A) such that the quantity A/N is less than about 200 .mu.m.sup.2 /cell. The porous boundary has a pore size, an ultimate strength, and a metabolic transit value that assures the survival of the cells during the critical ischemic period and afterward.

REFERENCES:
patent: 3967618 (1976-07-01), Zaffaroni
patent: 3993072 (1976-11-01), Zaffaroni
patent: 4011861 (1977-03-01), Enger
patent: 4266999 (1981-05-01), Baier
patent: 4298002 (1981-11-01), Ronel et al.
patent: 4306318 (1981-12-01), Mano et al.
patent: 4309776 (1982-01-01), Berguer
patent: 4309996 (1982-01-01), Theeuwes
patent: 4352883 (1982-10-01), Lim
patent: 4353888 (1982-10-01), Sefton
patent: 4374669 (1983-02-01), MacGregor
patent: 4378016 (1983-03-01), Loeb
patent: 4391909 (1983-07-01), Lim
patent: 4475916 (1984-10-01), Himmelstein
patent: 4487758 (1984-12-01), Goosen et al.
patent: 4508113 (1985-04-01), Malaney
patent: 4542539 (1985-09-01), Rowe et al.
patent: 4553272 (1985-11-01), Mears
patent: 4576608 (1986-03-01), Homsy
patent: 4601893 (1986-07-01), Cardinal
patent: 4657544 (1987-04-01), Pinchuk
patent: 4664669 (1987-05-01), Ohyabu et al.
patent: 4670286 (1987-06-01), Nyilas et al.
patent: 4673566 (1987-06-01), Goosen et al.
patent: 4686098 (1987-08-01), Kopchick et al.
patent: 4689293 (1987-08-01), Goosen et al.
patent: 4712553 (1987-12-01), MacGregor
patent: 4743252 (1988-05-01), Martin, Jr. et al.
patent: 4795459 (1989-01-01), Jauregui
patent: 4798585 (1989-01-01), Inoue et al.
patent: 4803168 (1989-02-01), Jarvis, Jr.
patent: 4804381 (1989-02-01), Turina et al.
patent: 4806355 (1989-02-01), Goosen et al.
patent: 4816339 (1989-03-01), Tu et al.
patent: 4871366 (1989-10-01), Von Recum et al.
patent: 4877029 (1989-10-01), Valentini et al.
patent: 4878913 (1989-11-01), Aebischer et al.
patent: 4892538 (1990-01-01), Aebischer et al.
patent: 4911717 (1990-03-01), Gaskill, III
patent: 4922926 (1990-05-01), Hirschberg et al.
patent: 4936317 (1990-06-01), MacGregor
patent: 4950483 (1990-08-01), Ksander et al.
patent: 4990138 (1991-02-01), Bacich et al.
patent: 5002661 (1991-03-01), Chick et al.
patent: 5024670 (1991-06-01), Smith et al.
patent: 5026365 (1991-06-01), Rossini et al.
patent: 5035891 (1991-07-01), Runkel et al.
patent: 5077215 (1991-12-01), McSuslan et al.
patent: 5100392 (1992-03-01), Orth et al.
patent: 5182111 (1993-01-01), Aebishcer et al.
patent: 5219361 (1993-06-01), von Recum et al.
patent: 5314471 (1994-05-01), Brauker et al.
Bioengineering in Development of the Hybrid Artificial Pancreas; C. K. Colton et al., Journal of Biomechanical Engineering, vol. 113, May 1991.
Texturing of Polymer Surfaces at the Cellular Level, Schmidt et al., Biomaterials, vol. 12, May, 1991.
Microtopography and Soft Tissue Response; Campbell et al., Journal of Investigative Surgery, vol. 2, pp. 51-74, 1989.
Macroporous Hydrogel Membranes for a Hybrid Artificial Pancreas. II. Biocompatibility; Klomp et al., Jrnl of Biomedical Mat. Res., vol. 17, 865-871 (1983).
Oxygen Tension Regulates the Expression of Angiogenesis Factor by Macrophages; Knighton et al., Science, 1981 vol. 221, Sep. 8, 1981.
Macrophage-derived Growth Factors in Wound Healing: Regulation of Growth Factor Production by the Oxygen Microenvironment; Knighton et al., AM. Rev. Respir. Dis. 1989; 140:1108-1111.
Activated Macrophages Induce Vascular Proliferation; Polverini et al., Nature, vol. 269, pp. 804-806, Oct. 27, 1977.
Tissue Reaction to Intraperitoneal Polymer Implants: Species difference and Effects of Corticoid and Doxorubicin, Christineson et al., Journal of Biomedical Materials Research, vol. 23, pp. 705-771, 1989.
Anderson J. "Inflammatory Response to Implants," vol. XXXIV Trans, Am. Soc. Artif. Intern. Organs, 1988 pp. 101-107.
Islet Immuno-Isolation: The Use of Hybrid Artificial Organs to Prevent Islet Rejection; Scrap et al., World J Surg 8, pp. 221-229 (1984).
The Tissue response to Implants and its Evaluation by Light Microscopy; Von Recum, Soft Tissue Histology pp. 364-378.
Characterization of Biomedical Polymer adherent Macrophages; Interlukin 1 Generation and Scanning Electron Microscopy Studies, Miller et al., Biomaterials, vol. 10, Apr. 1989, pp. 187-205.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Tissue implant systems and methods for sustaining viable high ce does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tissue implant systems and methods for sustaining viable high ce, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tissue implant systems and methods for sustaining viable high ce will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1384818

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.