Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1987-11-06
1989-11-21
Maples, John S.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
2603975, 424 9, A61K 4902, C07J 0000
Patent
active
048821411
ABSTRACT:
A process for detecting a presence of steroid receptors in tissue therapeutically and for treating certian tissue, especially tissue having estrogen receptors, includes the step of treating the tissue by injection, surface application or the like, with a labeled steroid. The labeled steroid may include a moiety which is readily imageable on a gamma radiation detector, on x-ray film, on a fluoroscope, through NMR devices or the like. An especially suitable labeled steroid has been found to be 16-.sup.123 I-17-beta-estradiol having a specific activity of greater than 2,000 curies per millimole and preferably at least 5,000 curies per millimole.
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Baranczuk Richard J.
Spicer Jay A.
Bio-Medical Research Laboratories, Inc.
Maples John S.
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