Tissue-equivalent and method for preparation thereof

Details Tissue-equivalent and method for preparation thereof Tissue-equivalent and method for preparation thereof

1982-05-26

1984-11-27

Rosen, Sam

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424177, A61K 3512, A61K 3536

Patent

active

044850964

ABSTRACT:
A tissue-equivalent, useful in the treatment of burns or other skin wounds and in the fabrication of prostheses, is disclosed which is prepared from a hydrated collagen lattice contracted by a contractile agent, such as fibroblast cells or blood platelets, to form tissue-equivalent. In one embodiment, a skin-equivalent can be fabricated by growing a layer of keratinocyte cells thereon. Both the keratinocyte cells and contractile agent may be derived from the potential recipient of the skin-equivalent.

REFERENCES:
patent: 4314380 (1982-02-01), Miyata et al.
Jelenska et al.-Thrombosis & Hemostasis, vol. 44, (Dec. 1980), pp. 161-163.
Bell et al.-J. of Inv. Dermatol., vol. 81, (1983), pp. 25-105.
Worst et al., J. of Nat. Cancer Inst., vol. 53, (1974), pp. 1061-1063.
Bell et al.-Am. Soc. Plastic & Reconstruct. Surgeons, vol. 67, No. 3, (Mar. 1981), pp. 386-392.
Coulomb et al.-J. of Inv. Dermat, vol. 81, (1983), pp. 75-78.
Bell et al.-Science, vol. 211, (1981), pp. 1052-1054.
Bell et al.-Proc. Nat. Acad. Sci., vol. 79, No. 3, (Mar. 1979), pp. 1274-1278.
Sarber et al.-Mechanisms of Ageing & Devel., vol. 17, (1981), pp. 107-117.
Hull et al., J. of Invest. Dermatol., vol. 81, (1983), pp. 436-438.
Hull et al.-J. of Invest. Dermatol, vol. 81, (1983), pp. 429-436.
Coulomb et al.-Brit. J. Dermatol. Supplement 1984.
Sher et al.-Transplantation, vol. 36, No. 5, (1983), pp. 552-557.
Ebendal-Zoon, vol. 2, (1974), pp. 99-104.
Stenzel et al.-Annual Rev. of Biophys. & Bioeng., vol. 3, (1974), pp. 231-253.
Elsdale et al.-J. Cell Biol., vol. 54, (1972), pp. 626-637.
Ehrmann et al.-J. Nat'l Canc. Inst., vol. 16, (1956), pp. 1375-1403.
Michalopoulos et al.-Exptl. Cell Res., vol. 94, (1975), pp. 70-78.
Gey et al.-Exptl. Cell Res., vol. 84, (1974), pp. 63-71.
Hillis et al.-Exptl. Cell Res., vol. 26, (1962), pp. 9-36.

Affiliated with

Also associated with

Rating

Tissue-equivalent and method for preparation thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tissue-equivalent and method for preparation thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tissue-equivalent and method for preparation thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2134209