Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2011-05-17
2011-05-17
Nguyen, Quang (Department: 1633)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S366000, C435S395000, C424S422000
Reexamination Certificate
active
07943378
ABSTRACT:
The present invention relates, in general, to tissue engineering and, in particular, to a method of extending the lifespan of cells suitable for use in vascular engineering.
REFERENCES:
patent: 6172210 (2001-01-01), Wiedmer et al.
patent: 6245566 (2001-06-01), Gearhart et al.
patent: 6399384 (2002-06-01), Jat
patent: 2002/0098166 (2002-07-01), Havemann et al.
patent: 2002/0136726 (2002-09-01), Anderson et al.
patent: 2003/0138945 (2003-07-01), McAllister et al.
patent: 2003/0175961 (2003-09-01), Herron
patent: 2004/0044403 (2004-03-01), Bischoff et al.
patent: WO 99/35245 (1999-07-01), None
Robinson et al. Seeding of vascular grafts with an immortalized human dermal microvascular endothelial cell line. Angiology (1995) vol. 46(2), pp. 107-113 (abstract only).
Robinson et al. Seeding of vascular grafts with an immortalized human dermal microvascular endothelial cell line. Angiology (1995) vol. 46(2), pp. 107-113.
Niklason et al. Functional arteries grown in vitro. Science (1999) vol. 284, pp. 489-493.
Berghella et al. Rversible immortalization of human myogenic cells by site-specific excision of a retrovirally transferred oncogene. Human Gene Therapy (1999) vol. 10, pp. 1607-1617.
Efrat et al. Cell replacement therapy for type 1 diabetes. Trends in Molecular Medicine. 8(7):334-339, Jul. 2002.
Dawson et al. Safety issues in cell-based intervention trials. Fertility and Sterility (2003) vol. 80(5), pp. 1077-1085.
Poh et al. Blood vessels engineered from human cells. Lancet (Jun. 2005) vol. 365, p. 2122-2124.
L'Heureux et al. (2001) “A human tissue-engineered vascular media: a new model for pharmacological studies of contractile responses.” FASEB J. 15:515-524.
Westerman et al. (1996) Proc. Natl. Acad. Sci. USA 93:8971-8976.
Minamino et al. (2001) 21:3336-3342.
Clontech Laboratories product information for pLNCX, published 2000, downloaded from http://clontech.com/images/pt/dis—vectors/PT3133-5.pdf Feb. 1, 2008.
Krump-Konvalinkova et al, “Generation of Human Pulmonary Microvascular Endothelial Cell Lines”, Laboratory Investigation 81(12):1717-1727 (2001).
Chen et al, “Production and Characterization of Human 293 Cell Lines Expressing the Site-Specific Recombinase Cre”, Somatic Cell and Molecular Genetics 22(6):477-488 (1996).
Eaton et al, “Immortalized Chromaffin Cells Disimmortalized with Cre/lox Site-Directed Recombination for Use in Cell Therapy for Pain after Partial Nerve Injury”, Experimental Neurology 175:49-60 (2002).
Niklason et al, “Morphologic and mechanical characteristics of engineered bovine arteries”, J. Vasc. Surg. 33:628-638 (2001).
Cao et al. “Telomerase activation causes vascular smooth muscle cell proliferation in genetic hypertension”, FASEB Journal 16(1):96-98 (2002).
Minamino and Kourembanas, “Mechanisms of Telomerase Induction During Vascular Smooth Muscle Cell Proliferation”, Circ. Res. 89:237-243 (2001).
Yang et al, “Human Endothelial Cell Life Extension by Telomerase Expression”, The Journal of Biological Chemistry 274(37):26141-26148(1999).
Niklason et al, “Lifespan extension in vascular tissue engineering”, In Vitro Cellular And Developmental Biology Animal 38(Abstract):4A (2002) & 2002 Congress On in Vitro Biology, Orlando, FL, USA, Jun. 25-29, 2002.
Niklason et al, “Functional Arteries Grown In Vitro”, Science 284:489-493 (1999).
L 'Heureux et al, “A completely biological tissue-engineered human blood vessel”, FSEB J. 12;47-56 (1998).
Klinger et al,. “Relevance and safety of telomerase for human tissue engineering”, PNAS 103(8):2500-2505 (2006).
L'Heureux et al, “Human Tissue Engineered Blood Vessel for Adult Arterial Revascularization”, Nat. Med. 12(3):361-365 (2006).
Schechnar et al, “In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse”, PNAS 97(16):9191-9196 (2000).
Koike et al, “Tissue engineering: creation of long-lasting blood vessels”, Nature 428(6979):138-9 (2004)—Abstract.
McKee et al. “Human arteries engineered in vitro”, EMBO reports 4(6):633-638 (2003).
Procol—Approval2.pdf file.
Koike et al, “Creation of long-lasting blood vessels”, Nature 428:138-139 (2004).
Wang et al, “Risky immortalization by telomerase”, Nature 405:755-756 (2000).
Cao et al, “Telomerase activation causes vascular smooth muscle cell proliferation in genetic hypertension”, The FASEB Journal express article 10.1096/fj.01-0447fje, Published online Nov. 14, 2001.
Urano et al, “Vascular smooth muscle cell outgrowth, proliferation, and apoptosis in young and old rats”, Atherosclerosis 146:101-105 (1999).
Noble et al, “Alterations in the p16INK4aand p53 tumor suppressor genes of hTERT-immortalized human fibroblasts”, Oncogene 23:3116-3121 (2004).
Bennett et al, “Cooperative Interactions Between RB and p53 Regulate Cell Proliferation, Cell Senescence, and Apoptosis in Human Vascular Smooth Muscle Cells From Atherosclerotic Plaques”, Circ. Res. 82:704-712 (1998).
Counter Christopher M.
McKee J. Andrew
Niklason Laura E.
Duke University
Nguyen Quang
Nixon & Vanderhye P.C.
LandOfFree
Tissue engineering does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tissue engineering, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tissue engineering will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2707502