Tissue engineered tendons and ligaments

Details Tissue engineered tendons and ligaments Tissue engineered tendons and ligaments

2005-01-11

2005-01-11

Isabella, David J. (Department: 3738)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Having means to promote cellular attachment

C623S013170

Reexamination Certificate

active

06840962

ABSTRACT:
Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.

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