Tissue-engineered bone repair using cultured periosteal cells

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone

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623 66, A61F 228, A61F 254

Patent

active

057002894

ABSTRACT:
Periosteal cells have been grown in cell culture and have been shown to have an osteoblastic phenotype, with production of osteocalcin and glycosaminoglycan. When seeded into polymeric implants, repair of critical size cranial defects was demonstrated and was confirmed by histology, biochemical assays, and radiodensitometry.

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