Chemistry: analytical and immunological testing – Including sample preparation – Stabilizing or preserving
Patent
1994-08-18
1996-07-02
Warden, Robert J.
Chemistry: analytical and immunological testing
Including sample preparation
Stabilizing or preserving
422 99, 422101, 436 63, 436183, 4352831, 4352841, 210473, 210474, 210477, 210482, 2104973, 248 94, G01N 136, C12M 100
Patent
active
055321682
ABSTRACT:
An apparatus and method to simplify and accelerate the transfer of tissue biopsy samples from fixative to automatic tissue processing cassettes comprises a strainer device and a preformed filter. The strainer device is constructed from a perforated material such as stainless steel screen and is substantially conical in shape. The device is provided with a support ring attached to an upper edge of the cone; the ring is designed for positioning the device on a fixative collection container and for attaching a convenient handle. The tip of the cone is truncated, providing a planar collection surface. A preformed filter, also of conical shape with a flattened tip matching the collection surface, is inserted into the strainer device. Fixative, containing tissue biopsy samples, is poured into the device, and the samples rest on the flat bottom and sides near the bottom while the fixative flows through into the fixative collection container. The filter is removed from the strainer device, and folded with upper regions of the filter being brought into contact with the samples on the flat filter bottom. The filter is placed into an opened cassette and the cassette is closed. After infiltration with paraffin, the cassette is opened and the filter is torn along a perforated line, thus releasing the infiltrated tissue samples.
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Soderquist Arlen
Warden Robert J.
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