Tissue augmentation material and method

Details Tissue augmentation material and method Tissue augmentation material and method

2006-06-13

2006-06-13

Azpuru, Carlos A. (Department: 1637)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S426000, C523S114000, C523S115000, C623S011110

Reexamination Certificate

active

07060287

ABSTRACT:
A permanent, biocompatible material for soft tissue augmentation. The biocompatible material comprises a matrix of smooth, round, finely divided, substantially spherical particles of a biocompatible ceramic material, close to or in contact with each other, which provide a scaffold or lattice for autogenous, three dimensional, randomly oriented, non-scar soft tissue growth at the augmentation site. The augmentation material can be homogeneously suspended in a biocompatible, resorbable lubricious gel carrier comprising a polysaccharide. This serves to improve the delivery of the augmentation material by injection to the tissue site where augmentation is desired. The augmentation material is especially suitable for urethral sphincter augmentation, for treatment of incontinence, for filling soft tissue voids, for creating soft tissue blebs, for the treatment of unilateral vocal cord paralysis, and for mammary implants. It can be injected intradermally, subcutaneously or can be implanted.

REFERENCES:
patent: 3527217 (1970-09-01), Gettig
patent: 3703575 (1972-11-01), Thiele
patent: 4107288 (1978-08-01), Oppenheim et al.
patent: 4123091 (1978-10-01), Cosentino et al.
patent: 4191747 (1980-03-01), Scheicher
patent: 4197846 (1980-04-01), Bucalo
patent: 4322398 (1982-03-01), Reiner et al.
patent: 4330614 (1982-05-01), Mayer et al.
patent: 4373217 (1983-02-01), Draenert
patent: 4440754 (1984-04-01), Sorenson
patent: 4619655 (1986-10-01), Hanker et al.
patent: 4657548 (1987-04-01), Nichols
patent: 4693986 (1987-09-01), Vit et al.
patent: 4776890 (1988-10-01), Chu
patent: 4795467 (1989-01-01), Piez et al.
patent: 4803075 (1989-02-01), Wallace et al.
patent: 4842603 (1989-06-01), Draenert
patent: 4849285 (1989-07-01), Dillon
patent: 5007940 (1991-04-01), Berg
patent: 5011495 (1991-04-01), Hollinger
patent: 5034352 (1991-07-01), Vit et al.
patent: 5035711 (1991-07-01), Aoki et al.
patent: 5067965 (1991-11-01), Ersek et al.
patent: 5075360 (1991-12-01), Fitt et al.
patent: 5116387 (1992-05-01), Berg
patent: 5126141 (1992-06-01), Henry
patent: 5140016 (1992-08-01), Goldberg et al.
patent: 5141561 (1992-08-01), Ledard et al.
patent: 5143724 (1992-09-01), Leshchiner et al.
patent: 5158573 (1992-10-01), Berg
patent: 5192802 (1993-03-01), Rencher
patent: 5204382 (1993-04-01), Wallace et al.
patent: 5246698 (1993-09-01), Leshchiner et al.
patent: 5258028 (1993-11-01), Ersek et al.
patent: 5266248 (1993-11-01), Ohtsuka et al.
patent: 5306302 (1994-04-01), Bauer et al.
patent: 5324775 (1994-06-01), Rhee et al.
patent: 5336263 (1994-08-01), Ersek et al.
patent: 5344452 (1994-09-01), Lemperle
patent: 5352715 (1994-10-01), Wallace et al.
patent: 5399351 (1995-03-01), Leshchiner et al.
patent: 5451406 (1995-09-01), Lawin et al.
patent: 5480644 (1996-01-01), Freed
patent: 5490984 (1996-02-01), Freed
patent: 5523291 (1996-06-01), Janzen et al.
patent: 5571182 (1996-11-01), Ersek et al.
patent: 5573771 (1996-11-01), Geistlich et al.
patent: 5591453 (1997-01-01), Ducheyne et al.
patent: 5626861 (1997-05-01), Laurencin et al.
patent: 5637101 (1997-06-01), Shillington
patent: 5702677 (1997-12-01), Shimp et al.
patent: 5709875 (1998-01-01), Lebugle et al.
patent: 5752974 (1998-05-01), Rhee et al.
patent: 5766618 (1998-06-01), Laurencin et al.
patent: 5792478 (1998-08-01), Lawin et al.
patent: 5827937 (1998-10-01), Agerup
patent: 5837752 (1998-11-01), Shastri et al.
patent: 5853398 (1998-12-01), Lal et al.
patent: 5854382 (1998-12-01), Loomis
patent: 5861176 (1999-01-01), Ducheyne et al.
patent: 6165514 (2000-12-01), Bockman et al.
patent: 2029338 (1991-05-01), None
patent: 643732 (1978-01-01), None
patent: 0196143 (1986-10-01), None
patent: 2 227 176 (1990-07-01), None
patent: 61101447 (1986-05-01), None
patent: 6211459 (1987-01-01), None
patent: 8304129 (1985-07-01), None
patent: 87/04110 (1987-07-01), None
patent: WO91/17777 (1991-11-01), None
patent: WO99/02107 (1999-01-01), None
“Artificial Urinary Sphincter & Periurethral Injections,” Appell, Rodney A., M.D.; Obstetrics and Gynecology Report, vol. 2, No. 3, pp. 334-342, 1990.
“Periurethral Teflon Injection for Urinary Incontinence,” Politano et al., Journal of Urology, pp. 180-183, vol. III, Feb., 1974.
“PMMA Microspheres for Intradermal Implanation: Part 1. Animal Research,” Lemperle et al.; Animal Research Ann. Plas. Surg., 1991; 26:57-63.
“Migration & Granulomatous Reaction After Periurethral Injection of Polytef (Teflon),” Malizia et al. JAMA, Jun. 22/29, 1984—vol. 251, No. 24.
“Pulmonary Migration Following Periurethral Polytetrafluoroethylene Injection for Urinary Incontinence,” Claes et al., Journal of Urology 142:821-822, 1989.
“Histologic Observation of Soft Tissue Responses to Implanted, Multifaceted Particles and Discs of Hydroxylapatite,” Drobeck et al., J. of Oral Maxillofac. Surg., 42:143-149, 1984.
“Soft Tissue Responses to Hydroxylapatite Particles of Different Shapes,” Misiek et al.; J. of Oral Maxillofac. Surg.; 42:150-160, 1984.
“Subcutaneous Tissue Responses in Rats to Injection of Fine Particles of Synthetic Hydroxyapatite Ceramic,” Shimizu, Shin-ichi; Biomedical Research, 9 (2) 95-111, 1988.
“Bioplastique: A New Textured Copolymer Microparticle Promises Permanence in Soft Tissue Augmentation,” Ersek et al.; Plastic and Reconstructive Surgery, Apr. 1991, pp. 693-701.
“Bioglass®—A Suspension for Treatment of Urinary Incontinence,” Ramer et al., 16thAnnual Meeting of the Society for Biomaterials, May 20-23, 1990.
“Hylan Gel for Soft Tissue Augmentation,” Larsen et al., 16thAnnual Meeting of the Society for Biomaterials, May 20-23, 1990.
Lehtenen et al., “Soft Tissue Response to Hydroxyapatite Particles of Different Shapes in Rabbit Tibia,”J. Oral Maxillofac. Surg., 1990, pp. 48:1075-1078.
“Remington's Pharmaceutical Sciences,” Gennaro, Ed., 18thEdition, 1990, pp. 1304-1305 and 1316.
Van Vlack et al., “Elements of Materials Science,”Addison Wesley(1964) pp. 379-380.
Dental Implants, in Bioceramics of Calcium Phosphate, Klaas deGroot, (ed), CRC Press, pp. 115-129 (1983).
Hench, “Ceramics in Substitutive and Reconstructive Surgery,”Elsevier Science Publishers B.V.(1991) pp. 259-274.
Caro et al., “The Mechanics of the Circulation,”Oxford University Press(1978) p. 156.

Affiliated with

Also associated with

Rating

Tissue augmentation material and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tissue augmentation material and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tissue augmentation material and method will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3628903