Tissue adhesives with modified elasticity

Details Tissue adhesives with modified elasticity Tissue adhesives with modified elasticity

2011-06-14

2011-06-14

Truong, Duc (Department: 1765)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Nitrogen-containing reactant

C528S310000

Reexamination Certificate

active

07960498

ABSTRACT:
An embodiment of the invention is a water soluble chain-extended polyamine product made by a process comprising reacting a multi-arm polyether amine with a bifunctional crosslinker of the formula: X1—R—X2. Another embodiment is a water soluble chain-extended polyamine product made by a process comprising reacting a multi-arm polyether having at least three arms and three electrophilic endgroups with a primary diamine crosslinker of the formula: NH2—R2—NH2, followed by treating of the chain-extended product so as to convert the remaining electrophilic endgroups to amine endgroups. Crosslinking of the chain-extended polyamine products with an oxidized polysaccharide provides useful tissue adhesives with modified elasticity, that provides greater compliance to underlying tissue, and improved stability in aqueous environments.

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