Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-10-31
2006-10-31
Carlson, Karen Cochrane (Department: 1653)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S350000, C530S353000, C530S354000, C530S356000, C530S360000, C530S362000, C530S363000, C530S365000, C530S367000, C424S443000
Reexamination Certificate
active
07129210
ABSTRACT:
A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive with the aldehyde cross-links to form a seal. The sealant is well suited for bonding tissue alone or in combination with a patch. The ratio between the aldehyde and the amino acid containing species is between 20:1 and 1:1 on an aldehyde moiety:amino acid or peptide subunit molar basis. Particularly strong seals are formed when the protein and cross-linking agent are present in a molar ratio of between 15:1 and 1:1.
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Browdie David A.
Cox David
DeLustro Frank
Lowinger Bruno
Lowinger Johan
Carlson Karen Cochrane
Covalent Medical, Inc.
Gifford, Krass, Groh Sprinkle, Anderson & Citkowski, P.C.
Tsay Marsha
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