Tissue adhesive

Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis

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424177, A61K 3514, A61K 3700

Patent

active

042985986

ABSTRACT:
A tissue adhesive on the basis of human or animal proteins has a content of factor XIII and fibrinogen, the ratio of factor XIII to fibrinogen, expressed in units of factor XIII per gram of fibrinogen, amounting to at least 80. Furthermore, it contains a plasminogen-activator-inhibitor or plasmin-inhibitor in an amount of 20 to 2,000 KIU per ml.

REFERENCES:
Matras et al., Wiener Medizinischen wochenschrift, No. 37, pp. 517-523 (1972).
Spangler et al., Wiener klinische wochenschrift, 85 (50), 827-829, (1973).
Spangler, Wiener klinische wochenschrift, Supplement 49, vol. 88, pp. 3-18 (1976).
Matras et al., Wiener klinische wochenschrift 90 (12) pp. 419-425 (Jun. 1978).
Stemburger, Thrombosis Research, vol. 12, No. 5, pp. 907-910, Pergammon Press (1978).

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