Tip to surface spacing for optimum dispensing controlled by a de

Details Tip to surface spacing for optimum dispensing controlled by a de Tip to surface spacing for optimum dispensing controlled by a de

1991-03-21

1992-09-01

Housel, James C.

Chemistry: analytical and immunological testing

Automated chemical analysis

Condition or time responsive

436 54, 436180, 422 63, 422 67, 422100, 7386301, 7386424, G01N 3502, G01N 3508, B01L 302

Patent

active

051438496

ABSTRACT:
A method for automatically adjusting a dispensing tip from a surface onto which liquid is to be dispensed, a proper distance that precludes the dispensing stream from puddling up, or from breaking apart. The method features the formation on the tip of a meniscus of a nominal small volume and advancing the tip and meniscus until the surface is contacted. The resulting decrease in pressure in the tip is measured, to trigger the tip to stop its advance and to start dispensing. In circumstances wherein the contacted surface is hydrophobic so as to ideally require a meniscus depth greater than the nominal depth, the tip is retreated from the surface, during dispensing, to the ideal depth.

REFERENCES:
patent: 4340390 (1982-07-01), Collins et al.
patent: 4347875 (1982-09-01), Columbus
patent: 4586546 (1986-05-01), Mezei et al.
patent: 4615360 (1986-10-01), Jacobs
patent: 4675301 (1987-06-01), Charneski et al.
patent: 4737344 (1988-04-01), Koizumi et al.
patent: 4794085 (1988-12-01), Jessop et al.
patent: 5059393 (1991-10-01), Quenin et al.

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