Tip part of a dosage vessel

Dispensing – Drop formers

Patent

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Details

222215, 222564, B65D 4718

Patent

active

049364987

DESCRIPTION:

BRIEF SUMMARY
The present invention concerns the tip part of a dosage vessel for the dosage of liquid dropwise through a downwardly directed tip part, which is provided with a capillary exhaust duct as well as with a neck duct wider than the exhaust duct, the liquid having access through said neck duct out of the vessel into the exhaust duct.
For the dosage of various solutions dropwise, plastic bottles made of flexible plastic, e.g. polyethylene, are commonly used, out of which liquid is applied dropwise through a small opening provided in the mouth of the bottle by pressing the sides of the bottle which has been turned upside down.
In particular in the application of eye drops, it would be important to be able to apply the drops as of a size as uniform as possible while avoiding excessively large drops. In prior-art dropping bottles, one of the problems has been that the drop may fall off the bottle even before the bottle has been pressed, or that several drops fall at a time.
It is known in prior art that the dropping of several drops at a time can be prevented by using a choke in the narrow exhaust duct passing to the exhaust opening. A tip part in which an exhaust duct provided with a narrower portion is used is described, e.g., in the U.S. Pat. No. 2,987,223. The narrower portion is located at the inner end of the exhaust duct.
It is also known that the outer diameter of the exhaust duct projecting outwards from the tip part affects the size of the drop that is formed. With the prior-art dropping bottles and with water solutions, it has been noticed that the drop size is about 35 . . . 50 .mu.1, as a rule about 40 . . . 50 .mu.1, when various eye drops are applied. It is also possible to reduce the drop size by adding to the liquid, some additive that lowers the surface tension.
A smaller drop size would be preferable, because on blinking of the eye, a major part of the drop applied to the eye is washed off the eye and ends up in the nasolacrimal duct and in the throat. Several eye drops may have detrimental side effects by this way. Of course, a smaller drop size would also be preferable out of the reason that the same bottle would be sufficient for a longer time of use. Moreover, a smaller drop size also permits a more accurately graded dosage when the dosage consists of several small drops.
When a bottle, e.g., in accordance with the U.S. Pat. No. 2,987,223 is used, the accuracy of dosage is deteriorated, among other things, by the fact that liquid often remains in the tip part, which liquid alters the drop size when drops are applied next time, e.g., by forming bubbles and splashes with air. This problem is harmful in particular when the drop size is reduced.
For allergy testing on the skin, smaller drops of uniform size are also needed, e.g. when various test patches are used.
The object of the present invention is to reduce the drop size with dropping bottles as well as to improve the accuracy of dosage. The tip part of a dosage vessel in accordance with the invention is characterized in that the neck duct contains an oblong member parallel to the neck duct.
During application of drops, the liquid moves outwards through the capillary exhaust duct, and no replacement air passes in. After the bottle has been, upon dosage, turned back to the standing position with its tip upwards, replacement air flows through the same duct from outside into the vessel.
In numerous tests it has been noticed that in a tip part in accordance with the invention the above oblong member in the neck duct guides the liquid and any air that may be contained in the liquid in the desired way back into the bottle after the application of drops, after the bottle has been turned to the standing position, whereby no liquid or foam consisting of liquid and air remains in the tip part. Thereby the reproductions of the droppings are optimal. When a tip part in accordance with the invention is used, the drop size can be reduced down to about 15 .mu.1, and even below that.
The invention and its details will be described in more detail in the foll

REFERENCES:
patent: 878668 (1908-02-01), Phelps et al.
patent: 1970688 (1934-08-01), Callahan
patent: 2832513 (1958-04-01), Tubin
patent: 2874881 (1959-02-01), Stull
patent: 2925200 (1960-02-01), Cabe
patent: 2987223 (1961-06-01), Armour

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