Time-resolved diffusion tomographic 2D and 3D imaging in highly

Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation

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600473, 600310, A61B 600

Patent

active

061085766

ABSTRACT:
A method for imaging objects in highly scattering turbid media. According to one embodiment of the invention, the method involves using a plurality of intersecting source/detectors sets and time-resolving equipment to generate a plurality of time-resolved intensity curves for the diffusive component of light emergent from the medium. For each of the curves, the intensities at a plurality of times are then inputted into the following inverse reconstruction algorithm to form an image of the medium: wherein W is a matrix relating output at source and detector positions r.sub.s and r.sub.d, at time t, to position r, .LAMBDA. is a regularization matrix, chosen for convenience to be diagonal, but selected in a way related to the ratio of the noise, <nn>to fluctuations in the absorption (or diffusion) X.sub.j that we are trying to determine:

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