Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1978-12-08
1982-10-26
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
424 21, 424 47, A61J 300, A61J 310, A61K 954
Patent
active
043561667
ABSTRACT:
A time-release chemical delivery system in which a bioactive compound is attached to a polymeric biodegradable carrier by a hydrolyzable bond is disclosed. The bioactive compound can either be bound directly to the polymer or be attached to the polymer via a spacer group. The composition of the system is particularly effective for delivering medication systemically to a host animal over a prolonged period of time after being surgically implanted or injected subcutaneously. Biodegradable condensation polymers having reactive pendant groups, for example, poly-L-(glutamic acid), or derivatized poly-L-(glutamic acid) are effective as polymeric carriers.
REFERENCES:
patent: 3639516 (1972-02-01), Sarfaty et al.
patent: 3950282 (1976-04-01), Gilbert et al.
patent: 4122129 (1978-10-01), Casey et al.
Anderson James M.
Feijen Jan
Gregonis Donald E.
Kim Sunj-Wan
Peterson Robert V.
Roberts Elbert L.
University of Utah
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