Tie1-binding ligands

Details Tie1-binding ligands Tie1-binding ligands

2008-03-25

2008-03-25

Chan, Christina (Department: 1644)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S133100, C424S141100, C424S143100, C435S007100, C530S387100, C530S388100, C530S388150, C530S388220, C530S391300

Reexamination Certificate

active

10916840

ABSTRACT:
Tie1 is a receptor tyrosine kinase protein that includes a transmembrane domain. Tie1 is present on endothelial cells. This disclosure described antibodies that bind to Tie1, including ones that inhibit endothelial cell activity.

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