Tie ligand homologues

Details Tie ligand homologues Tie ligand homologues

1997-09-19

2000-02-29

Spector, Lorraine

Chemistry: molecular biology and microbiology

Vector, per se

536 231, 536 235, 435325, 4352523, 43525411, 435 691, 530350, C12N 1512, C12N 1511, C12N 510, C07K 14475

Patent

active

060308311

ABSTRACT:
The present invention concerns isolated nucleic acid molecules encoding the novel TIE ligands NL2, NL3 and FLS139, the proteins encoded by such nucleic acid molecules, as well as methods and means for making and using such nucleic acid and protein molecules.

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Maisonpierre et al., "Angiopoietin-2, a Natural Antagonist for Tie2 that Disrupts in vivo Disrupts in vivo Angiogenesis" Science277:55-60 (Jul. 4, 1997).

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