Tick chitinase

Details Tick chitinase Tick chitinase

2003-02-28

2009-02-10

Graser, Jennifer E (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S234100, C424S094100, C435S004000, C435S007400, C530S350000

Reexamination Certificate

active

07488488

ABSTRACT:
A novel chitinase, a polynucleotide encoding the same, a vector and a transformant comprising the polynucleotide, an antibody against the chitinase, and a screening method for screening a substance capable of modifying the chitinase, are disclosed. According to the chitinase, polynucleotide, or vector, it is possible, for example, to exterminate ticks, or to treat or prevent tick-borne infections such as piroplasmosis, Q fever, or viral encephalitis.

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Database UniProt [Online], Oct. 1, 2002, “Chitinase”, XP002428764, retrieved from EBI accession No. UNIPROT: Q8MY79, Database accession No. Q8MY79. Database EMBL [Online], Jul. 30, 2002, “Haemaphysalis longicornisCht mRNA for chitinase, complete cds”, XP002428765, retrieved from EBI accession No. EMBL: AB074977, Database accession No. AB074977.
Database UniProt [Online], Dec. 1, 2001, “LD45559p”, XP002428766, retrieved from EBI accession No. UNIPROT: Q960M0, Database accession No. Q960M0. Database EMBL [Online], Aug. 27, 2001, “Drosophila melanogaster LD45559 full length cDNA”, XP002428767, retrieved from EBI accession No. EMBL: AY051988, Database accession No. AY051988.
You, Myungjo, et al., “Identification and Molecular Characterization of a Chitinase from the Hard TickHaemaphysalis longicornis”, The Journal of Biological Chemistry, Mar. 7, 2003, pp. 8556-8563, vol. 278, No. 10, XP002428759, ISSN: O021-9258, The American Society for Biochemistry and Molecular Biology, Inc.

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