Thyroid hormone analysis by mass spectrometry

Chemistry: analytical and immunological testing – Nuclear magnetic resonance – electron spin resonance or other...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C436S086000, C436S169000, C436S171000, C436S500000, C422S071000

Reexamination Certificate

active

07618827

ABSTRACT:
Methods, systems and kits for the simultaneous or sequential analysis of one or more hormones by mass spectrometry are disclosed. The methods require minimal sample size and minimal preparation time. The methods include ionizing the hormones and analyzing the hormones by mass spectrometry. In addition, methods, systems and kits for the simultaneous or sequential analysis of thyroid hormones are disclosed including ionization of the thyroid hormones in the negative mode using an electrospray source.

REFERENCES:
patent: 4741897 (1988-05-01), Andrews et al.
patent: 2004/0235188 (2004-11-01), Soldin
patent: WO 01/88548 (2001-11-01), None
patent: 0246772 (2002-06-01), None
patent: 0246772 (2002-06-01), None
De Brabandere, Veronique I. et al., Isotope Dilution-Liquid Chromatograhy/Electrospray Ionization-Tandem Mass Spectrometry for the Determination of Serum thyroxine as a Potential Reference Method, 1998, Rapid Communications in Mass Spectroscopy, 12, 1099-1103.
Thienpone Linda M. et al., Isotope Dilution-Gas Chromatography/Mass Spectrometry and Liquid Chromatography/Electrospray Ionization-Tandem Mass Spectrometry for the Determination of Triiodo-L-Thyronine in Serum, 1999, Rapid Communications in Mass Spectroscopy, 13, 1924-1931.
Kissmeyer, Anne-Marie et al., Determination of the vitamin D analog EP 1089 (seocalcitol) in human and pig serum using liquid chromatography-tandem mass spectrometry, 2000, Journal of Chromatography B, 740, 117-128.
Jonsson, Bo A.G., et al., Determination of cotrisol in human saliva using liquid chromatography-electrospray tandem mass spectrometry, 2003, Joumal of Chromatography B, 784, 63-68.
Leinonen, Antti, et al., Liquid chromatography/mass spectrometry in steroid analysis-optimization and comparison of three ionization techniques: electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization, 2002, Journal of Mass Spectrscopy, 37, 693-698.
Fredline, Victoria F et al., A Reference Method for the Analysis of Aldosterone in Blood by High-Performance Liquid Chromatography-atmospheric Pressure Chemical Ionization-Tandem Mass Spectrometry, 1997, Analytical Biochemistry, 252, 308-313.
Vogeser, Michael et al., Determination of Serum cotrisol by Isotope-Dilution Liquid-Chromatography Electrospray Ionization tandem Mass Spectrometry with On-line Extraction, 2001, Clin Chem Lab, 39(10), 944-947.
Draisci, R. et al, Quantitation of anabolic hormones and their metabolites in bovine serum and urine by liquid chromatography-tandem mass spectrometry, 2000, Journal of Chromatography A, 870, 511-522.
Siekmann, L. “Measurement of thyroxine in human serum by isotope dilution mass spectrometry. Definitive methods in clinical chemistry, V” Biomedical and Environmental Mass Spectrometry, vol. 14. No. 11, Nov. 1987, pp. 683-688.
Siekmann, L., “Measurement of thyroxine in human serum by isotope dilution mass spectrometry. Definitive methods in clinical chemistry, V”, Biomedical and Environmental Mass Spectrometry, vol. 14, No. 11, Nov. 1987, pp. 685-688.
Thienpont, L.M., et al., “Development of a new method for the determination of thyroxine in serum based on isotope dilution gas chromatography mass spectrometry”, Biol Mass Sprectrom, vol. 23, No. 8, 1994, pp. 475-482.
De Brabandere, Vi et al., “Isotope dilution-liquid chromatography/electrospray ionization-tandem mass spectrometry for the determination of serum thyroxine as a potential reference method”, Rapid Commun Mass Spectrom, vol. 12, No. 16, 1998, pp. 1099-1103.
Kosaka, Takeo et al., “Analysis of thyroid hormones in health foods by LC/MS” Shokuhin Eiseigaku Zasshi, vol. 43, No. 4, Aug. 2002, pp. 225-229.
Tai, SSC et al., “Candidate reference method for total thyroxine in human serum: use of isotope dilution liquid chromatography-mass spectrometry with electrospray ionization”, Clinical Chemistry, vol. 48, No. 4, 2002, pp. 637-642.
Chang, Y-C et al., “Quantitative measurement of male steroid hormones using automated on line solid phase extraction liquid chromatography tandem mass spectrometry and comparison with radioimmunoassay”, Analyst, vol. 128, No. 4, Apr. 1, 2003, pp. 363-368.
International Search Report for PCT/CA2004/000555, dated Jul. 2, 2004.
Soukhova, N. et al., “Isotope Dilution Tandem Mass Spectrometric Method for T4/T3” Clinica Chimica Acta, Elsevier BV, Amsterdam, NL, vol. 343, No. 1/02, Jan. 1, 2004, pp. 185-190.
Gu Jianghong et al. “Simultaneous quantification of free triiodothyronine and free thyroxine by isotope dilution tandem mass spectrometry”, Dec. 2007, Clinical Biochemistry, vol. 40, NR. 18, pp. 1386-1391.
International Search Report for PCT/US 05/38232 dated Sep. 13, 2007.
European Search Report for EP 05 85 1243 dated Mar. 11, 2009.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Thyroid hormone analysis by mass spectrometry does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thyroid hormone analysis by mass spectrometry, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thyroid hormone analysis by mass spectrometry will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4129031

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.