Thymosin β4 derivatives and use thereof

Details Thymosin β4 derivatives and use thereof Thymosin β4 derivatives and use thereof

2006-07-14

2010-10-19

Landsman, Robert (Department: 1647)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S399000

Reexamination Certificate

active

07816321

ABSTRACT:
The present invention relates to thymosin β4 (Tβ4) derivatives, Gly-Tβ4 and Ala-Tβ4. The present invention further relates to a pharmaceutical composition comprising the said Tβ4 derivatives. The present invention also relates to the use of said Tβ4 derivatives in manufacture of a medicament for treatment of skin lesion, heart injury, corneal lesion and/or coronary heart disease. The present invention further relates to a method of treatment for skin lesion, heart injury, corneal lesion and/or coronary heart disease by using the said Tβ4 derivatives.

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Nie et al., “Expression of thymosin beta 4 mRNA expression in keloid tissues and fibroblasts cultured from keloid and its significance” Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 17(2): 80-83, Feb. 2005 (English Abstract, 1 page.).
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