Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1980-06-16
1981-10-27
Phillips, Delbert R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424177, C07C10352, A61K 3700
Patent
active
042972760
ABSTRACT:
Two related polypeptides, thymosin .beta..sub.3 and thymosin .beta..sub.4, have been isolated from Thymosin fraction 5. These peptides have been characterized and sequenced. Thymosin .beta..sub.3 has 50 amino acid residues while thymosin .beta..sub.4 has 43 amino acid residues corresponding identically to the amino terminal 43 amino acids of thymosin .beta..sub.3. The compounds have useful biological activity as evidenced by their ability to induce terminal deoxynucleotidyl transferase (TdT) positive cells in T-cell populations. The invention described herein was made in part in the course of work under a grant or award from the Department of Health, Education and Welfare.
REFERENCES:
patent: 4079127 (1978-03-01), Goldstein et al.
Goldstein Allan L.
Low Teresa L. K.
Gould George M.
Hoffman-La Roche Inc.
Phillips Delbert R.
Saxe Jon S.
Wilson John B.
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