Thrombus detection using radiolabelled disintegrins

Details Thrombus detection using radiolabelled disintegrins Thrombus detection using radiolabelled disintegrins

1992-10-19

1995-01-10

Kepplinger, Esther M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

514 12, 424 9, A61K 4902, G01N 3353

Patent

active

053806468

ABSTRACT:
Radiolabelled polypeptides derived from the Viperidae disintegrins are provided as well as a method for the detection of venous and arterial thrombi, pulmonary emboli and tumors or abscesses that have a thrombus component. Compositions suitable for parenteral administration comprising the radiolabelled polypeptides and a pharmaceutically acceptable carrier are also provided.

REFERENCES:
patent: 5066592 (1991-11-01), Huang et al.
Gould et al., Proc. Soc. Exp. Bio. Med. 195:168 (1990).
Knight et al., J. Nucl. Med. 31:757 (abstr.) (1990).
Knight, L. C., Sem. Nucl. Med. 20:52 (1990).

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