Thrombospondin receptor binding peptides

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 11 to 14 amino acid residues in defined sequence

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530328, 530329, 530330, A61K 3702

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active

053996674

ABSTRACT:
Novel short peptides are disclosed that bind to the thrombospondin 1 receptor, which preferably have 5-13 amino acid residues which share the tripeptide Val-Val-Met and have the following sequences: RFYVVMWKQVTQS (Seq ID No. 1) and fragments thereof containing the minimal sequence RFYVVM, (Seq ID No. 3) and FIRVVMYEGKK (Seq ID No. 4) and fragments thereof containing the minimal sequence IRVVM (Seq ID No. 5).

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Dixit et al., Proc. Natl. Acad. Sci. 82, 3472-3476 (1985).

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