Thrombosis treatment with fibrinolytics and prostacyclins

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases

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424 9464, 514530, 514822, 514824, A61K 3754, A61K 37547, A61K 31215

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active

053167660

ABSTRACT:
The combination of a fibrinolytic and a prostacyclin analogue is very useful for thrombosis treatment, especially to avoid subsequent rethrombosis.

REFERENCES:
patent: 4496745 (1985-01-01), Amemiya et al.
patent: 4839169 (1989-06-01), Whittle
Chem. Abst., 103:98516r, 1985.
Schumacher et al., "Augmentation of Streptokinase-Induced Thrombolysis by Heparin and Prostacyclin", Journal of Cardiovascular Pharmacology, 7:739-746, 1985.
FASEB 68th Annual Meeting APS, ASPET, AAP, AIN, St. Louis, Mo., Apr. 1-6, 1984, Proceedings, Coronary Pharmacology Abstracts, p. 335, No. 297, Schumacher et al., "Streptokinase (SK) Thrombolysis in Dogs: Potentiation by Heparin (H) and Prostacyclin (PGl.sub.2)".
Blasko et al., Drugs Exptl. Clin. Res., IX, (7), 505-506 (1983).
Szczeklik et al., Thrombosis Research, 29, 655-660 (1983).

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