Thromboresistant materials and methods for making same

Details Thromboresistant materials and methods for making same Thromboresistant materials and methods for making same

1991-01-15

1991-10-01

Nutter, Nathan M.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

530811, 530812, 530813, 530814, 530815, 530816, 523112, C08G 6348, C08G 6391

Patent

active

050534530

ABSTRACT:
Thromboresistant materials are disclosed comprising hirudin or hirudin derivatives covalently linked to support materials such that the resultant composition has substantially the same biological activity as hirudin. Methods for making such compositions are also disclosed.

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patent: 4734097 (1988-03-01), Tanabe et al.
patent: 4742157 (1988-05-01), Yamanaka et al.
patent: 4746731 (1988-05-01), Bohn et al.
Ito et al., "Immobilization of CGP39393 (Hirudin), a Specific Thrombin Inhibitor, on Artificial Surfaces", Circulation Supplement, Abstracts from the 61st Scientific Sessions of the American Heart Association, Part II, vol. 78, No. 4, Oct. 1988.

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