Thromboresistant coating for defoaming applications

Details Thromboresistant coating for defoaming applications Thromboresistant coating for defoaming applications

1994-10-28

1996-07-30

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 21, 536 553, 536124, 523112, 604 4, 604317, A61L 3300, A61K 31725

Patent

active

055411673

ABSTRACT:
A composition for coating medical blood contacting surfaces comprises a mixture of an anticoagulant and a defoaming agent. The coating composition is applied by either dipping the device into a solution containing the mixture or by spraying the mixture onto the surface. Alternatively, the surface can be sequentially dip coated and/or sprayed with the individual components. In a preferred embodiment, the anticoagulant is a quaternary ammonium complex of heparin, preferably stearyldimethylbenzyl ammonium heparin, and the antifoaming agent is a mixture of polydimethylsiloxane and silicon dioxide.

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