Thromboresistant coated medical device

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure

Reissue Patent

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C427S002100, C428S034700, C428S035200, C428S035700, C428S036910, C428S425600, C428S425800, C428S442000, C428S447000, C428S450000, C428S451000, C428S458000, C428S463000, C428S480000, C428S522000

Reissue Patent

active

RE039438

ABSTRACT:
Coatings are provided in which biopolymers may be covalently linked to a substrate. Such biopolymers include those that impart thromboresistance and/or biocompatibility to the substrate, which may be a medical device. Coatings disclosed herein include those that permit coating of a medical device in a single layer, including coatings that permit applying the single layer without a primer. Suitable biopolymers include heparin complexes, and linkage may be provided by a silane having isocyanate functionality.

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