Thrombin inhibitors

Details Thrombin inhibitors Thrombin inhibitors

1998-12-01

1999-12-21

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546118, A61K 31435, C07D47104

Patent

active

060049766

ABSTRACT:
A compound which inhibits human thrombin and where has the structure ##STR1## such as ##STR2##

REFERENCES:
Bantick, et al., "New Non-Peptide Angiotensin II Receptor Antagonists . . . ," Bioorg. Med. Chem. Letters, vol. 4, No. 1, pp. 127-132 (1994).
Brown, et al., "Design of Orally Active, Non-Peptidic Inhibitors of Human Leukocyte Elastase," J. Med. Chem., vol. 37, No. 9, pp. 1259-1261 (1994).

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