Thrombin inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S264100, C514S266220, C514S266230, C514S300000, C514S301000, C514S302000, C514S115000, C544S279000, C544S284000, C546S114000, C548S152000, C548S217000, C548S304700, C548S360100

Reexamination Certificate

active

07112590

ABSTRACT:
The invention relates to compounds that are heterocyclic derivatives of dipeptides and dipeptides mimetics and pharmaceutically acceptable salts thereof. The compounds are used as thrombin inhibitors

REFERENCES:
patent: 5510369 (1996-04-01), Lumma et al.
patent: 5523308 (1996-06-01), Costanzo et al.
patent: 5811402 (1998-09-01), Klimkowski et al.
patent: 5827866 (1998-10-01), Costanzo et al.
patent: WO 98/47876 (1998-10-01), None
Das J et al. “Thrombin Active Site Inhibitors”, Bioorganic & Medicinal Chemistry, GB, Elsevier Science Ltd, vol. 3, No. 8, 1995, pp. 999-1007, XP000995766.
International Search Report, Jul. 9, 2001.

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